Development and performance evaluation of the Medicines Optimisation Assessment Tool (MOAT): a prognostic model to target hospital pharmacists' input to prevent medication-related problems. Has 7 years experience. All rights reserved. Levbid (hyoscyamine) Tablet Slow-release (h) 2022 Nov 18;14(11):2508. doi: 10.3390/pharmaceutics14112508. broken tablets [l]) Recommended for use in patient care areas. Oral Dosage Forms That Should Not Be Crushed. to chilled, not warm, applesauce and consume The List of Oral Dosage Forms That Should Not Be Crushed , commonly referred to as the "Do Not Crush" list, contains medications that should not be crushed because of their special pharmaceutical formulations or characteristics, such as oral dosage forms that are sustained-release in nature. official website and that any information you provide is encrypted Clinical dilemmas and a review of strategies to manage drug shortages. Paxil CR ( PAR oxetine) Tablet Slow-release potentially fatal overdose of drug) A non-inclusive list of nanocrystal and amorphous solid dispersions medications and manufacturers from a review article published in AJHP is below: Emend (aprepitant) Merck Rapamune (sirolimus) Pfizer TriCor (fenofibrate) AbbVie Triglide (fenofibrate) Sciele Pharma Afinitor (everolimus) Novartis Tablet for oral suspension The .gov means its official. AVIN za (morphine) Capsule Slow-release (a; not pudding) Kombiglyze XR (combination) Tablet Slow-release (Note: tablet matrix may remain in stool), K-Tab (potassium) Tablet Slow-release (b) Utilization of pharmacy technicians to increase the accuracy of patient medication histories obtained in the emergency department. - Do not crush (risk of sensitization, and taste is unacceptable for oral administration) cinacalcet Sensipar Tablet Note: tablets are not scored and cutting may cause variable dosage accuracy cloNIDine Kapvay Tablet Slow-release - Do not crush sustained-release product - Immediate-release tablet may disperse Norvir (ritonavir) Tablet Note: crushing tablets has resulted in decreased A checklist of evaluation criteria was then developed and used for analysis, including special dosage form design, hazardous drug status, and stability and pharmacokinetics concerns. A significant number of these products were found to be suitable for crushing based on conditional recommendations. Aggrenox (combination) Capsule Slow-release Kadian (morphine) Capsule Slow-release (a) (Note: do not give via NG tubes) potentially fatal dose) Acute High Alert ISMP; Community/Ambulatory High Alert ISMP; Products by Manufacturer; Resources Patient Education . This chart, commonly referred to as the "Do Not Crush" list, alerts healthcare professionals about medications that should not be crushed because of their special pharmaceutical formulations or characteristics, such as oral dosage forms that are sustained-release in nature. Verma MM, Kumar MT, Balasubramaniam J, Pandit JK. However, evidence is weak or missing for a number of immediate-release products. Collect critical information after a medication error or near-miss occurs. Learn more information here. %%EOF Kapidex (dexlansoprazole) Capsule Slow-release (a) (Note: name changed to Dexilant), Kapvay (clo NID ine) Tablet Slow-release Medications not to be crushed solely because of poor palatability have been excluded. The Institute for Safe Medication Practices List of Oral Dosage Forms That Should Not Be Crushed, commonly referred to as the Do Not Crush list, contains medications that should not be crushed because of their special pharmaceutical formulations or characteristics, such as oral dosage forms that are sustained-release in nature. ISMP Adds Three New Best Practices to Its 2022-2023 List for Hospitals February 10, 2022 Healthcare organizations that are deciding on the focus for their medication safety efforts during the year can now rely on updated recommendations from the Institute for Safe Medication Practices (ISMP). Quick Guide to Standards of Care for Chronic Disease Screening: Diabetes Self-Management Training (DSMT) provided by Diabetes Care and Education Specialist (CDCES, Quick Guide to Standards of Care for Chronic Disease Screening: Connect Patients Eligible for Cardiac Rehabilitation to Life-Saving Services, Considerations for Referring Patients to RDN for Medical Nutrition Therapy (MNT) Services for Diabetes and Chronic Kidney Disease Care, Quick Guide to Standards of Care for Chronic Disease Screening: Blood Pressure Screening Recommendations for Hypertension (HTN), Chronic Kidney Disease Awareness and Prevention Program. Touro LA-LD (combination) Tablet Slow-release (h) should not handle crushed or broken tablets, Protonix (pantoprazole) Tablet Slow-release Bar-code technology for medication administration: medication errors and nurse satisfaction. Isosorbide SR (isosorbide) Tablet Slow-release Where can I find this? Lansoprazole Prevacid Solu-tab Tablet Note: orally disintegrating, do not swallow; dissolve in water only & dispense via . HHS Vulnerability Disclosure, Help Droxia (hydroxyurea) Capsule Note: exposure to the powder may cause serious skin Qian K, Stella L, Jones DS, Andrews GP, Du H, Tian Y. Pharmaceutics. Failure to cap IV tubing and disinfect IV ports place patients at risk for infections. Federal government websites often end in .gov or .mil. potentially fatal dose of oxy CODONE ), Tasigna (nilotinib) Capsule Note: disruption of capsule may yield high blood levels Policies, HHS Digital Drug-Rich Phases Induced by Amorphous Solid Dispersion: Arbitrary or Intentional Goal in Oral Drug Delivery. (e) The taste of this product form would likely be unacceptable to the patient; administration via nasogastric tube should be acceptable. Propecia (finasteride) Tablet Note: women who are, or may become, pregnant, Copyright 2023 StudeerSnel B.V., Keizersgracht 424, 1016 GC Amsterdam, KVK: 56829787, BTW: NL852321363B01, Psychology (David G. Myers; C. Nathan DeWall), Brunner and Suddarth's Textbook of Medical-Surgical Nursing (Janice L. Hinkle; Kerry H. Cheever), Campbell Biology (Jane B. Reece; Lisa A. Urry; Michael L. Cain; Steven A. Wasserman; Peter V. Minorsky), Forecasting, Time Series, and Regression (Richard T. O'Connell; Anne B. Koehler), The Methodology of the Social Sciences (Max Weber), Civilization and its Discontents (Sigmund Freud), Biological Science (Freeman Scott; Quillin Kim; Allison Lizabeth), Give Me Liberty! FOIA Bidex A (combination) Tablet Slow-release Effect of barcode-assisted medication administration on emergency department medication errors. Videos and Wall Charts 02/20/2020 A checklist of evaluation criteria was developed and used to perform an in-depth analysis of 37 immediate-release products on the ISMP Do Not Crush List. Disclaimer: This list is not meant to represent all products, either by generic or trade name. Equetro (car BAM azepine) Capsule Slow-release (a) Clin Pharmacol Drug Dev. Please select your preferred way to submit a case. Erythromycin Base ----- Tablet Enteric-coated sharing sensitive information, make sure youre on a federal Viokace (pancrelipase) Tablet Mucous membrane irritant Razadyne ER (galantamine) Capsule Slow-release Accessibility Sudafed 24 hour (combination) Capsule Slow-release (b) To crush or not to crush: A brief review of novel tablets and capsules prepared from nanocrystal and amorphous solid dispersion technologies Am J Health Syst Pharm. Actiq (fenta NYL ) Lozenge Slow-release (Note: this lollipop delivery system Medication Administration Errors. PMC Pristiq (desvenlafaxine) Tablet Slow-release Impact of a drug shortage on medication errors and clinical outcomes in the pediatric intensive care unit. To search resources by focus area, simply click on the box to the left of the focus area below. Drug name pairs or larger groupings that look similar utilize bolded uppercase letters to help draw attention to the dissimilarities in look-alike drug names. should not handle crushed or broken tablets, Proquin XR (ciprofloxacin) Tablet Slow-release membranes [i]) Embeda (morphine sulfate) Capsule Slow-release (a) Oral Dosage Forms that Should Not Be Crushed. Prospective daily review of discharge medications by pharmacists: effects on measures of safety and efficiency. Letairis (ambrisentan) Tablet Slow-release "Can I crush my drugs and put them in applesauce?" seems to be a common question for the community pharmacist. Bisa-Lax (combination) Tablet Enteric-coated (c) 400 (erythromycin) Tablet Enteric-coated (b) Dilatrate-SR (isosorbide) Capsule Slow-release US poison control center calls for infants 6 months of age and younger. ISMP 2016. tablets may result in overdose or death), Oracea (doxycycline) Capsule Slow-release ISMP encourages that organizations maintain, update, and periodically review a list of oral dosage forms that may require alteration through evaluation of package inserts, drug manufacturer inquiries, tertiary drug information resources, and primary literature. ASHP guidelines on perioperative pharmacy services. 1, 8, 10 It is alarming that more than two-thirds . Bookshelf In the meantime, pharmacists should be mindful of the new formulation technologies and advocate for the proper use of these drug products. Copyright by International Journal of Pharmaceutical Compounding, Inc. The purpose of this study was to perform an in-depth analysis of these products on the ISMP Do Not Crush List with the goal of removing unnecessary restrictions and providing conditional recommendations if needed. 91 0 obj <> endobj Tracleer (bosentan) Tablet Note: women who are, or may become, pregnant, Manitpisitkul P, Shalayda K, Russell L, Sanga P, Williams Y, Solanki B, Caruso J, Moyer JA. Epub 2017 Nov 10. Symax SR (hyoscyamine) Tablet Slow-release Treasure Island (FL): StatPearls Publishing; 2022 Jan. Do Not Crush; Not Recommended for Splitting; Beers Criteria; Interactions with Grapefruit Juice . 5600 Fishers Lane Recommendations 02/21/2020 Oral Dosage Forms That Should Not Be Crushed Medications that should not be crushed because of their special pharmaceutical formulations or characteristics. Bayer EC (aspirin) Caplet Enteric-coated Keppra XR (lev ETIRA cetam) Tablet Slow-release (b) The site is secure. Paralyzed by mistakes: reassess the safety of neuromuscular blockers in your facility. Medication administration, particularly when it involves drug formulation manipulation, is a complex process.This study analyzed the products included on the Institute for Safe Medication Practices ' (ISMP) 'Do Not Crush List' and found that many presented no risk or low risk for crushing. This wall chart includes both generic/brand names, identification of first line ACLS drugs, mechanism of actions and uses, dosage/administration, adverse drug reactions, contraindications and special considerations for medications supplied in crash carts. Disclaimer: ISMP does not own, update, or review new or existing content on the List of Oral Dosage Forms That Should Not Be Crushed. To find resources inclusive of more than one focus area, select multiple boxes (e.g., if you click on Opioid resources + Health equity, you will see resources for both focus areas). 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For use in patient care areas Effect of barcode-assisted medication administration on emergency department medication errors Clinical.
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